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Abstract

Pain perception is intricately linked to genetic variability, influencing how individuals perceive and respond to pain stimuli. Genetic factors contribute significantly to variations in pain sensitivity and resilience, shaping an individual's experience of discomfort and their ability to cope with it. Understanding these genetic underpinnings is pivotal in tailoring effective, personalized pain management approaches that account for individual differences in pain perception. Current research delves into identifying specific genetic determinants, such as variations in neurotransmitter receptors and ion channels involved in nociception pathways. These findings not only deepen our understanding of pain mechanisms but also hold promise for developing targeted therapies that can optimize pain relief while minimizing adverse effects. Integrating genetic insights into clinical practice could revolutionize pain management, offering more precise and efficient treatment strategies tailored to the genetic profiles of patients.