The Value of Placebos to Individualize Pain Therapy via A New Singleblind Test Paradigm Identifying Responders on Topical Analgesic Interventions
Received Date: Mar 12, 2018 / Accepted Date: Mar 19, 2018 / Published Date: Mar 29, 2018
Abstract
Pain management should be individualized for each patient as much as possible, and the use of a placebo in the clinical practice can help. The treatment with compounded topical analgesics holds a great promise for such individualized therapy, due to the fast response of patients after applying cream containing adequate concentrations of an active pharmaceutical ingredient. We present and discuss a new single-blinded placebo-controlled test paradigm, enabling the physician to quickly differentiate between responders and non-responders, and to further explore the concentration-effect response. This way the placebo assists in selecting the optimal pain treatment, and such use should be regarded as beneficial for patients and ethical correct.
Keywords: Ethics; Analgesia; Topicals; Phenytoin; Amitriptyline; Analgesic cream
Citation: Hesselink JMK, Kopsky DJ (2018) The Value of Placebos to Individualize Pain Therapy via A New Single-blind Test Paradigm Identifying Responders on Topical Analgesic Interventions. J Pain Relief 7: 313. Doi: 10.4172/2167-0846.1000313
Copyright: © 2018 Hesselink JMK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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