Understanding Pharmacokinetic Variability: Implications for Therapy
Received Date: Jun 03, 2024 / Published Date: Jun 28, 2024
Abstract
Pharmacokinetic variability among individuals poses significant challenges in clinical practice, influencing drug efficacy and safety. This variability arises from genetic, physiological, and environmental factors, impacting drug absorption, distribution, metabolism, and excretion (ADME). Understanding these complexities is crucial for tailoring therapy to individual patients, optimizing drug dosing, and minimizing adverse effects. This article explores the implications of pharmacokinetic variability on therapeutic outcomes, highlighting the importance of personalized medicine and strategies such as pharmacogenetic testing and therapeutic drug monitoring (TDM) in clinical practice.
Citation: Ferreira R (2024) Understanding Pharmacokinetic Variability: Implicationsfor Therapy. J Pharmacokinet Exp Ther 8: 248.
Copyright: © 2024 Ferreira R. This is an open-access article distributed underthe terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.
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