Xenobiotic Metabolism: Mechanisms and Implications for Drug Metabolism and Toxicology
Received Date: Oct 02, 2024 / Published Date: Oct 29, 2024
Abstract
Xenobiotic metabolism is the process by which foreign compounds, such as drugs, environmental pollutants, and toxins, are chemically modified and eliminated from the body. This complex process involves enzymatic reactions primarily occurring in the liver, where phase I and phase II enzymes play critical roles in transforming xenobiotics into more water-soluble forms for excretion. Understanding xenobiotic metabolism is essential for drug development, as it influences drug efficacy, toxicity, and interactions. This article explores the key mechanisms of xenobiotic metabolism, the enzymes involved, and the factors that influence individual variations in metabolism. The role of xenobiotic metabolism in pharmacokinetics, drug-drug interactions, and the potential for toxicity are also discussed, highlighting the significance of this process in therapeutic applications and public health
Citation: Tamal B (2024) Xenobiotic Metabolism: Mechanisms and Implications for Drug Metabolism and Toxicology. J Cell Mol Pharmacol 8: 244 Doi: 10.4172/jcmp.1000244
Copyright: © 2024 Tamal B. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Share This Article
Recommended Journals
黑料网 Journals
Article Tools
Article Usage
- Total views: 109
- [From(publication date): 0-0 - Mar 10, 2025]
- Breakdown by view type
- HTML page views: 78
- PDF downloads: 31
