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Atherosclerosis is a cardiovascular disorder in which plaque gets deposited on inner walls of arteries which leads to narrowing and thickening of them. It leads to many cardio related disorders like coronary heart disease, stroke, peripheral arterial disease, chronic kidney disease, atherosclerosis diagnosis.  The plaque occludes the coronary artery by which blood flow to the heart is stopped, and this leads to heart attack. It is done by coronary reserve flow (CFR), serum makers and by imaging studies like , computed topography, coronary angiography.