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Down syndrome (DS) is caused by an extra copy of the long arm of human chromosome 21 (HSA21) and the increased expression, due to dosage, of HSA21 encoded genes. In addition to intellectual disability, all individuals with DS develop the neuropathology of Alzheimer’s Disease (AD) by age 30-40. The amyloid precursor protein gene, APP, that is ... Read More»
Aaron Block, A. Ranjitha Dhanasekaran, Md. Mahiuddin Ahmed and Katheleen J Gardiner
Research Article: J Alzheimers Dis Parkinsonism 2014, 4:138
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