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Aβ Metabolism and the Role of APOE in Alzheimer's Disease
Disturbance of the production and clearance of Aβ in the brain is the main cause of memory and cognition decline and contributes strongly to the development of AD. In human, APOE gene has three isoforms, ε2, ε3 and ε4, with APOE ε4 as the most risk gene among them. In the development of AD pathophysiology, ApoE4... Read More»
Yue Miao Yin, Jing Du and Zhao Wang
Mini Review: J Alzheimers Dis Parkinsonism 2016, 6:285
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