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Biography

Kebreten Manaye is an Associate Professor in the Department of Physiology and Biophysics at the Howard University College of Medicine where she has been a faculty member for eleven years. After earning her medical degree from the University Of Aristotle School Of Medicine in Thessalonica Greece. Dr Manaye joined the Department of Psychiatry at the University of Texas, Southwestern Medical Center in Dallas as a postdoctoral fellow in 1986 In 1990 she became an assistant professor in the department before moving to Howard University in 1999. Her publications have appeared in journals such as the Journal of Comparative Neurology Biological Psychiatry and Neuropharmacology. She is an active member of several professional organizations including American Association for the Advancement of Science AAAS the Society for Neuroscience International Alzheimer Association International Brain Research Organization and the New York Academy of Sciences. She currently serves as an Associate Editor for the Journal of Alzheimer Disease and she also serves on the Board of Directors for the International Behavioral Research Press and Sinq Neuroimaging Systems Inc

Research Interest

Dr. Manaye research program focused on understanding the mechanisms that underlie neurological illnesses associated with brain aging. For these studies, she has used a diverse range of stereological, neuroimaging, molecular, biochemical, and behavioral approaches to understand normal aging of the brain, neuropathology of aging, and comparative work aimed at elucidating neuronal mechanisms of neurodegenerative disorders, including Alzheimer and Parkinson disease, and to develop potential approaches to prevent or delay the onset of these disorders. Her main research interest is to investigate the mechanisms of neuropathology and treatments of neurodegenerative disorders using in vivo and in vitro models. She has found a mouse model that exhibits similar neuropathology to that found in these neurodegenerative disorders. She has further found that 17 estradiol is an effective mediator of neuroprotection in this model. Her long term goal of these studies is the development of novel strategies for the therapeutic management of patients afflicted with AD and PD.

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