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Abstract

Chondrosarcoma, a rare malignant bone tumor originating from cartilage cells, presents diagnostic and therapeutic challenges due to its diverse clinical manifestations and propensity for metastasis. This article presents a clinical algorithm for the diagnosis and management of chondrosarcoma, integrating advances in imaging techniques, histopathological examination, molecular analysis, and multidisciplinary treatment strategies. The algorithm outlines a systematic approach to clinical evaluation, imaging studies, biopsy, histopathological analysis, and treatment selection, emphasizing the importance of a multidisciplinary tumor board in tailoring individualized treatment plans. Surgical resection remains the cornerstone of localized disease management, with adjuvant therapies and targeted agents playing adjunctive roles in select cases. Surveillance and follow-up strategies are crucial for detecting disease recurrence and guiding timely interventions. By incorporating evidence-based practices and collaborative decision-making, this clinical algorithm aims to optimize outcomes and enhance the quality of care for patients with chondrosarcoma