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Abstract

Background: This study investigated the effects of diet, exercise, and vagus nerve stimulation (VNS) methods on body composition, functional capacity, and blood parameters in the short term.

Methods: We performed our research in obese individuals(N:90) aged 18-65 years, who were stage I, II, and III according to WHO. Laboratory measurements and evaluation scales of individuals in the Diet, Exercise, and VNS groups were compared. Anthropometric changes were recorded as well as changes in functional capacity (6-minute walk test(6MWT)), muscle strength (hand grip strength test); stair climbing test(SCT), food choice (Excessive food cravings Questionnaire(FCQ), Visual analog scale(VAS), and quality of life(The 36-Item Short Form Health Survey questionnaire(SF-36)).

Results: A weight loss of 4%-10% in total body weight (4.7–10.4 kg) in a 4-week period improved anthropometric features, functional capacity, and quality of life (p <0.05). Considering the parameters and tests examined in the study, although there were no statistically significant differences between the groups, it was observed that there was a positive effect on health status in all 3 groups compared to the beginning of the study. Weight loss was statistically significant in DG compared to other groups (p <0.05). Percentage distribution of weight loss, respectively, Diet Group(DG): 10%; Exercise Group(EG): 6%; VNS Group: 4%.

Conclusion: 3 different methods - diet, exercise, and VNS - that we have examined in a 4-week period were effective in creating weight loss. Although there is no significant weight loss with auricular VNS, it has been observed as a result of the scale data that there may be a behavioral change in terms of appetite/food choice orientation. We think that auricular VNS can be used alone or in addition to other weight loss methods in the treatment of obesity. There is a need for long-term research on this three methods related to body weight change.