Polyglandular Type III C Syndrome Associated with Double-Seronegative Myasthenia Gravis
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Copyright: © 2019 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
The neuroimmunologic diseases are a challenge to health services. We described the evolution of MG in the patient presented as proximal weakness, fatigue, chest pain, ptosis, arthralgia, diplopia and dysphonia. Besides that, the patient presented Systemic Lupus Erythematosus (SLE), positivity/reagent for antinuclear antibody (ANA), anti-thyroid peroxidase antibodies (anti-TPO antibodies) and anti-glutamic acid decarboxylase (anti-GAD). Because of the other comorbidities, the hypothesis of the Polyglandular Autoimmune Syndrome (PAS) III was made, represented by the combination of a clinical diagnosis of an autoimmune thyroiditis with Diabetes Mellitus type 1 (DM1).
