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Abstract

Orthopedic oncology, the specialized field focusing on the management of bone and soft tissue tumors, has witnessed a remarkable shift in cancer treatment approaches with the emergence of immunotherapy. Immunotherapy utilizes the body’s immune system to recognize and attack cancer cells, offering a promising alternative to traditional treatment modalities. This short communication explores the evolving role of immunotherapy in orthopedic oncology and its transformative impact on cancer care. We discuss the principles behind immunotherapy, including immune checkpoint inhibitors, adoptive cell therapies, and cancer vaccines, and their specific applications in orthopedic malignancies. Furthermore, we examine the clinical advancements and ongoing research in the field, highlighting the potential of immunotherapy to improve patient outcomes and revolutionize cancer treatment strategies in orthopedic oncology. By embracing this paradigm shift, orthopedic oncologists can pave the way towards more effective and personalized therapeutic interventions, providing renewed hope for patients facing these challenging tumors.