Research Article
Synthesis of A Novel Ferrocene Derivative and Cytotoxicity to A549, HCT116 and MCF-7 Cell Lines
Jianping Yong1*, Xiao Wang2, Xiaoyuan Wu2, and Canzhong Lu1,3*1Xiamen Institute of Rare-earth Materials, Chinese Academy of Sciences, Xiamen, 361021, China
2Department of Pharmacy, Bao’an People’s Hospital Affiliated to Southern Medical University, Shenzhen, Guangdong, 518101, China
3Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China
- *Corresponding Author:
- Jianping Yong
Xiamen Institute of Rare-earth Materials, Chinese Academy of Sciences
Xiamen, 361021, China
Fax: +86-59183705794
Email: czlu@fjirsm.ac.cn
Canzhong Lu
Xiamen Institute of Rare-earth Materials
Chinese Academy of Sciences, Xiamen, 361021
China
Fax: +86-59183705794
E-mail: jpyong@fjirsm.ac.cn
Received date: November 04, 2016; Accepted date: January 02, 2017; Published date: January 04, 2017
Citation: Yong J, Wang X, Wu X, Lu C (2017) Synthesis of A Novel Ferrocene Derivative and Cytotoxicity to A549, HCT116 and MCF-7 Cell Lines. J Infect Dis Ther 5:1000311. doi:10.4172/2332-0877.1000311
Copyright: © Yong J, et al This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Based on our previous results, a ferrocene derivative 1 was synthesized in this study and characterized by 1H NMR, 13C NMR, MS and XRD methods. And then, the cytotoxicity to A549, HCT116 and MCF-7 cell lines was evaluated using the MTT method. The results showed that this compound exhibited good cytotoxicity to A549, HCT116 and MCF-7 cell lines.
