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ISSN: 2155-6199

Journal of Bioremediation & Biodegradation
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Alginate/�?潞-Carrageenan and alginate/gelatin composite hydrogel beads for controlled drug release of curcumin

7th International Conference and Exhibition on Biopolymers and Bioplastics

Jinu George

Sacred Heart College Thevara, India

Posters & Accepted Abstracts: J Bioremediat Biodegrad

DOI:

Abstract
Hydogel beads based on natural polymers like alginate, �?潞-carrageenan and gelatin represent an efficient scaffold for targeted hydrophobic drug delivery. We report herein the development and characterization different formulations of hydrogel systems based on the above mentioned polymers having adequate properties as drug delivery matrices. Different combinations of alginate/�?潞carrageenan and alginate/gelatin hydrogel beads were developed and drug release properties were compared using curcumin as a model drug. Morphology, swelling behavior and analytical characterization of the matrices were carried out using IR spectroscopy and SEM. Alginate/�?潞-carrageenan hydrogel beads with 50:50 weight ratio exhibited higher swelling and better drug release percentage than compared to other beads. Encapsulation efficiency and drug release behavior of different formulations of alginate/�?潞-carrageenan and alginate/gelatin, indicates that the polymer blends synthesized possess considerable potential in pharmaceutical and medicinal applications.
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