ISSN: 2572-4983
Neonatal and Pediatric Medicine
黑料网
Our Group organises 3000+ Global Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ 黑料网 Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
黑料网 Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers
Recommended Conferences
Vancouver, Canada
Toronto, Canada
Toronto, Canada
Citations : 303
Indexed In
- Google Scholar
- RefSeek
- Hamdard University
- EBSCO A-Z
- ICMJE
Useful Links
Recommended Journals
Related Subjects
Share This Page
Childhood infections and risk of type 1 diabetes in Tlemcen, Northwest Algeria
32nd World Pediatrics Conference
S Khater, A Aouar, H Hamdaoui, A Moussouni, Z Moqaddem, D Belkhatir, H Bouazza and N Chabni
University of Abou Beker Belkaid, AlgeriaTlemcen University Teaching Hospital, Algeria
Posters & Accepted Abstracts: Neonat Pediatr Med
Abstract
Background: Type 1 diabetes is an autoimmune multifactorial disease caused by a complex interaction of genetic and environmental factors. Several studies have shown that viral infections cause the onset of type 1 diabetes by inducing immune responses that can damage β- cells.Aim: This study aims to examine the interaction between type 1 diabetes and childhood viral infections in children of Tlemcen in northwest Algeria.
Patients and Methods: This is a case-control study of a population of 338 children under the age of 15 years, including 137 diabetic children and 201controls children, living in Tlemcen in Western Algeria. The data were collected using questionnaires submitted by a physician to the parents of the cases and controls, from February to May 2018. The data were analyzed by a logistic regression processed by Minitab.16 software.
Results: The total frequency of exposure to childhood infections (varicella, measles, rubella, mumps or tonsillitis) in early childhood is higher in diabetic children (81.75%) than in controls (66.66%), p=0.003. The risk of type 1 diabetes for children exposed to a single infection was only statistically significantly for rubella (p=0.016), odds ratio: confidence interval (CI) (OR: 3.73, 95% CI, 1.28-10.88). However, if two or more infections was contracted during the years before the onset of diabetes, the risk increases significantly (p=0.000), (OR: 3.33, 95% CI, 1.92-5.78).
Conclusion: The high prevalence of infectious diseases among young children in Tlemcen鈥檚 population may explain the development of type 1 diabetes in children in this region.
