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The presentation concerns PRP and Stem Cell (both bone marrow and adipose) injections for musculoskeletal conditions
in an office setting. Indications are given as to which type of cell and technique to use to accomplish repair. Stem cells,
both bone marrow-derived (BMAC) and adipose are used for the more difficult problems. PRP injections are utilized for the
less severe problems. Indications are given when to use Stem Cells verses PRP and when to use both. The newest concepts in
stem cell science are presented. These concepts include the clinical use of MUSE cells, exosomes and Blastomere like stem cells.
Basic science of both PRP and stem cells are discussed. This presentation defines what constitutes an effective PRP preparation.
Myths concerning stem cells are dispelled. One myth is that mesenchymal stem cells are the most important stem cell. This was
the initial interpretation of Arnold Caplan the father of mesenchymal stem cell science. Caplan now feels that MSCs have an
immunomodulation capacity which may have a more profound and immediate effect on joint chemistry and biology. We now
learn in the talk that the hematopoietic stem cells are the drivers of tissue regeneration. Also discussed are adjuncts used which
enhance the results. These therapies include supplements, LED therapy, lasers, electrical stimulation and cytokine therapy. The
scientific rationale is presented for each of these entities as to how they have a direct on stem cells.