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Purpose: Alpha-7-nicotinic acetylcholine receptor (α7-nAChR) positive allosteric modulators (PAMs) are a potential disease modifying treatment for Alzheimer’s disease, as exemplified by the approved drug galantamine. However, clinical development of this class of compounds has stalled due to poor efficacy and severe adverse reactions, li... Read More»
Aaron McMurtray, Erin Saito, Shannon Tsang, Anna Lee and Sean Ekins
: Clin Pharmacol Biopharm 2020, 9:1
10.4172/2167-065X.1000192Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article
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