Journal of Mucosal Immunology Research
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Suzanne Jones
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Spp1+ Macrophages Trained by Platelets Activate Myofibroblasts in Fibrosis in a Cxcl4-dependent way
Independent of the initial insult, fibrosis is a common final stage of chronic organ injury that destroys tissue architecture and results in organ failure. Here, we identify a profibrotic macrophage population that increases following organ injury and is characterised by the expression of Spp1, Fn1, and Arg1. We determine the chemokine (C-X-C motif... Read More»
: J Mucosal Immunol Res 2022, 7: 171
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