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Yutaka Osawa
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Background: Non-clinical and clinical studies showed efficacy of thrombomodulin alfa for disseminated intravascular coagulation, and its potential efficacy for severe sepsis and coagulopathy. Thrombomodulin alfa is excreted primarily via the kidney and renal function is known to affect the clearance. However the dosing adjustments for patie... Read More»
Shinichiro Shirae, Yutaka Osawa, Thomas C Marbury and Kazuhisa Tsuruta
Research Article: Clin Pharmacol Biopharm 2016, 5:159
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