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Disturbances of Tryptophan Metabolism and Risk of Depression in HCV Patients Treated with IFN-Alpha
Depression is a common side-effect of interferon (IFN)-alpha treatment of hepatitis C virus (HCV) infection and melanoma. Disturbances of tryptophan (TRP) metabolism might contribute to development of IFN-alpha–associated depression due to IFN-alpha-induced activation of indoleamine 2,3-dioxygenase (IDO), a rate-limiting enzyme of TRP– ... Read More»
Oxenkrug GF, Turski WA, Zgrajka W, Weinstock JV, Ruthazer R and Summergrad P
Research Article: J Infect Dis Ther 2014, 2:131
DOI:
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