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(Japan is an Asian country which is in the Asia Pacific region and a neighbor of P.R. China, North Korea, South Korea and Russia. The word Japan refers to “sun origin”, therefore, this country is known as "Land of the Rising Sun").

(Geographically, the whole country consists of four major islands, they are, Honshu, Hokkaido, Kyushu and Shikoku. Altogether, the country is having 6,852 islands. The country is having a chain of islands (archipelago) with numerous composite volcanos. Politically, Japan is part of the UN along with other global alliances such as G7, G8, and the G20).

 After huge suffering from atomic bombing during World War II, Japan excelled in all arenas of research and development. According to world nominal GDP computation, Japan is having third-largest economy and fourth in the world as per power purchasing parity.

 Noble Laureates from this country are in the field of    Clinical science recently awarded to Dr. Takaaki Kajita in Physics for the year 2015, and more the 24 Noble laureates had served for the Japan in Clinical sciences

 Japan has become a more attractive market for foreign and domestic pharmaceutical companies and the contract research organizations (CRO) that support them. Challenges remain, however, and this paper summarizes current PMDA processes, compares Japanese and international standards for Good Clinical Practice (GCP), examines cultural factors that may affect clinical trials and discusses the role of CROs in the management of in Japan.

 

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