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South Africa is located in the southern end of Africa and neighboring by Botswana, Lesotho, Mozambique, Namibia, Swaziland, and Zimbabwe.

South Africa is the 25th largest country in the world by land area, and with close to 53 million people, is the world's 24th most populous nation. It is the southernmost country on the mainland of the Old World or the Eastern Hemisphere.South Africa occupies the southern tip of Africa, its coastline stretching more than 2,500 kilometers (1,600 miles) from the desert border with Namibia on the Atlantic coast southwards around the tip of Africa and then north to the border with Mozambique on the Indian Ocean.

The economy of South Africa is the second largest in Africa, behind Nigeria. South Africa accounts for 24 percent of Africa's gross domestic product, and it is ranked as an upper-middle-income economy by the World Bank. Main industries include mining, gold, chromium, automobile assembly, metal working.

Max Theiler was a South African-American virologist and doctor. He was awarded the Nobel Prize in Physiology or Medicine in 1951 for developing a vaccine against yellow fever in 1937, becoming the first African-born Nobel laureate. Allan MacLeod Cormack was a South African American physicist who won the 1979 Nobel Prize in Physiology or Medicine for his work on X-beam registered tomography (CT).The South African Medical Research Council was established in 1969 with the aim to deliver on a mandate to promote the improvement of the health and the quality of life of the population through research. Numerous medical journals are published from South Africa on clinical research and public health studies. Research at the SAMRC focuses on the ten highest causes of mortality in South Africa and includes TB, HIV, chronic diseases, alcohol and drug abuse, and women’s health. The South African Medical Journal is published by the South African Medical Association, which represents most medical professionals in South Africa.

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