Case Report
18F-FDG PET/CT for Diagnosis of Castleman Disease: A Case Report
Sayumi Suzuki1, Karin Takeda1, Takemichi Okada2, Hitoshi Yamazaki3, Yasutaka Senpuku4 and Hiroaki Yokomori1*
1Department of Internal Medicine and Radiology Kitasato University Medical Center, Kitamoto, Saitama, Japan
2Department of Pathology, Kitasato University Medical Center, Kitamoto, Saitama, Japan
3Department of Radiology, Kitasato University Medical Center, Kitamoto, Saitama, Japan
4Ageo Central General Hospital, Saitama, Japan
- *Corresponding Author:
- Hiroaki Yokomori, M.D.
Kitasato University Medical Center, 6-100 Arai
Kitamoto-shi, Saitama, 364-8501, Japan
Tel: +81-48-593-1212
Fax: +81-48-593-1239
E-mail: yokomori@insti.kitasato-u.ac.jp
Received date: May 18, 2016; Accepted date: May 25, 2016; Published date: May 31, 2016
Citation: Suzuki S, Takeda K, Okada T, Yamazaki H, Senpuku Y, et al. (2016) 18F-FDG PET/CT for Diagnosis of Castleman Disease: A Case Report. J Gastrointest Dig Syst 6:431. doi:10.4172/2161-069X.1000431
Copyright: © 2016 Suzuki S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License; which permits unrestricted use; distribution; and reproduction in any medium; provided the original author and source are credited.
Abstract
A 73-year-old man was admitted to our hospital with fever of unknown origin (FUO). Laboratory findings showed high levels of C-reactive protein (25.99 mg/dL) and interleukin-6 (IL-6) (14.7 pg/mL). Computed tomography revealed right lateral pleural effusion and ascites. 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT revealed intense tracer accumulation in the cervical and para-aortic nodal chains, and lymph node excisional biopsy showed mixed type Castleman disease. Prednisolone and IL-6 receptor antibody, tocilizumab, achieved dramatic results. FDG PET/CT is a valuable modality for assessment of etiology in patients with FUO. This can help identify suitable glands for excisional biopsy in such cases.
