Case Report
Capsaicin 8% Patch Compared with Pregabalin in the Treatment of Nondiabetic Peripheral Neuropathic Pain: Elevate Trial
Antonio Alcántara Montero* | |
Chronic Pain Unit,José María Álvarez Health Center. Don Benito (Badajoz), Spain. Member of the Working Group Pain SEMERGEN, Spain | |
Corresponding Author : | Antonio Alcántara Montero Chronic Pain Unit. José María Álvarez Health Center Don Benito (Badajoz) 06400 Don Benito (Badajoz), Spain Tel: 34 650 732 962 E-mail: a.alcantara.montero@hotmail.com |
Received January 07, 2016; Accepted January 19, 2016; Published January 22, 2016 | |
Citation: Alcántara A (2016) Capsaicin 8% Patch Compared with Pregabalin in the Treatment of Nondiabetic Peripheral Neuropathic Pain: Elevate Trial. J Pain Relief 5:227. doi:10.4172/2187-0846.1000227 | |
Copyright: © 2016 Alcántara A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
Abstract
Conventional treatments for peripheral neuropathic pain may be restricted by factors such as systemic side effects, interactions with other drugs, the slow onset of action, the need for dose adjustments and multiple daily doses. Recently it has been published in the European Journal of Pain a simultaneous non-inferiority study comparing patch capsaicin 8% with pregabalin (flexible dose optimized) in adult patients with nondiabetic peripheral neuropathic pain. According to this study, topical treatment with capsaicin patch 8% was not inferior to pregabalin. This means that the patch capsaicin 8% could be another treatment option for patients with Nondiabetic peripheral neuropathic pain, especially those who are very sensitive to the side effects of systemic medications or for those not wishing oral drug treatment daily.