Review Article
Exercise Training and Insulin Resistance: A Current Review
| Tyler E Keshel1 and Robert H Coker1,2* | |
| 1Institute of Arctic Biology, University of Alaska-Fairbanks, Fairbanks, AK, USA | |
| 2Center for Translational Research in Aging and Longevity, Department of Geriatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA | |
| Corresponding Author : | Robert H. Coker, Ph.D Institute for Arctic Biology University of Alaska-Fairbanks 902 North Koyukuk Drive, Fairbanks, AK, 99775-7000, USA Tel: 907-474-6701 Fax: 907-474-5700 E-mail: CokerRobert@uams.edu |
| Received: July 14, 2015 Accepted: July 22, 2015 Published: July 30, 2015 | |
| Citation: Keshel TE, Coker RH (2015) Exercise Training and Insulin Resistance: A Current Review. J Obes Weight Loss Ther S5:003. doi: 10.4172/2165-7904.S5-003 | |
| Copyright: © 2015 Keshel TE, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | |
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Abstract
There is a general perception that increased physical activity will improve glucose homeostasis in all individuals. While this is an attractive concept, this conclusion may be overly simplistic and even misleading. The topic was reviewed extensively over 30 years ago and it was concluded that acute exercise enhances glucose uptake. However, in some cases the chronic influence of interventions utilizing exercise may have little effect on glucose metabolism. Moreover, insulin resistance often returns to near baseline levels within a couple of days following cessation of the exercise bout; leaving the overall effectiveness of the intervention in question. Since improving glucose homeostasis should be the focal endpoint of any intervention designed to mitigate the overwhelming degree of insulin resistance in individuals at risk for metabolic disease, it is essential to evaluate the key components of a successful approach.
