Research Article
Pilot Case Series Demonstrating Unsuspected Ulceration in Perforated Ileum from Typhoid Fever
O. Kenneth Johnson*University of Malawi College of Medicine, Malawi
- Corresponding Author:
- O. Kenneth Johnson, Lecturer
Consultant Surgeon
University of Malawi College of Medicine, Malawi
Tel: +265881082440
E-mail: mailto:okjohnsonsj@jesuits.net
Received date: September 01, 2015; Accepted date: June 10, 2016; Published date: June 16, 2016
Citation: Johnson OK (2016) Pilot Case Series Demonstrating Unsuspected Ulceration in Perforated Ileum from Typhoid Fever. J Gastrointest Dig Syst 6:445. doi:10.4172/2161-069X.1000445
Copyright: © 2016 Johnson OK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
A recent case series of patients with suspected typhoid fever presenting with peritonitis and evidence of perforation were treated with simple closure, exteriorization of the perforated segment, and resection with ostomy formation. Resection with ostomy formation has been successful in severely advanced cases. The series has demonstrated two previously unreported features of the disease – multiple severe ulcerations throughout the distal ileum and multiple ulcerations in the cecum. Furthermore initial observation suggests a rapid return towards normal of systemic inflammatory response scores when resection was carried out.
