The Impact of Gut Microbiota on Host Obesity
Received Date: Nov 11, 2018 / Accepted Date: Jan 23, 2018 / Published Date: Jan 30, 2018
Abstract
Obesity is a critical medical condition present in the twenty-first century. Multiple factors contribute to its aetiology. Among those factors, the gut microbiota contribution is larger. Changes in the composition of two main phyla (increased Firmicutes and decreased Bacteroidetes) impact on mechanisms such as lipid metabolism and inflammation. Obese individuals indicate higher Firmicutes: Bacteroidetes ratio than their lean counterparts. Daily intake of high-fat diet also alters the gut microbiota composition. Nevertheless, direct bacterial influence in these mechanisms is still indistinct. Therefore, further investigations are required, which will also help to improve therapeutic strategies than those being used nowadays to treat obesity.
Keywords: Gut microbiota; Obesity; Gastrointestinal tracts; Gut lumen; Hypertension
Citation: Manchanayake LN (2019) The Impact of Gut Microbiota on Host Obesity. J Gastrointest Dig Syst 9: 591. Doi: 10.4172/2161-069X.1000591
Copyright: © 2019 Manchanayake LN, This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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