Research Article
Treatment Results of Anal Cancer: A Single-institution Long-term Experience
Anna Hemer, Annika Holmqvist, Gunnar Adell and Maria Albertsson*
Division of Oncology, Department of Clinical and Experimental Medicine, Faculty of Medicine and Health Sciences, County Council of Östergötland, Linköping University, 581 85 Linköping, Sweden
- Corresponding Author:
- Maria Albertsson
Division of Oncology, Department of Clinical
and Experimental Medicine, Faculty of Medicine
and Health Sciences, County Council of Östergötland
Linköping University, 581 85 Linköping, Sweden
Tel: +46 (0) 10 103 0000
E-mail: Maria.albertsson@regionostergotland.se
Received Date: Feb 9, 2016, Accepted Date: Mar 15, 2016, Published Date: Mar 22, 2016
Citation: Hemer A, Holmqvist A, Adell G, Albertsson M (2016) Treatment Results of Anal Cancer: A Single-institution Long-term Experience. J Gastrointest Dig Syst 6:402. doi:10.4172/2161-069X.1000402
Copyright: © 2016 Hemer A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Background: Anal and perianal cancer is a rare form of cancer. In this study we report results obtained using external beam radiotherapy with or without concurrent chemotherapy in the treatment of anal cancer. It is a singleinstitute long-term evaluation of 138 patients.
Methods: Retrospective analysis of 138 patients treated with radiotherapy (RT) with or without chemotherapy (CT) for an anal carcinoma (T1-4N0-N3M0).
Results: Overall Survival (OS) was 75% and Disease-free Survival (DFS) 68%. Interruptions in treatment were associated with a lower rate of survival.
Conclusion: This study confirms the outcomes of RT with or without CT in the treatment of anal cancer. High rates of side effects imposed tailored CT and RT as well as improved radiation techniques and better chemotherapy regimens.
