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Introduction: Misuse of antibiotics is one the most common
reason for drug resistant HAI and increased mortality in
intensive care units, more so in the neonatal units. There is
an urgent need to optimize the use of antibiotics across all
neonatal settings.
Aim: To rationalize antibiotic consumption in our unit
Methodology: In this observational study we evaluate the
effects of introduction and implementations of an antibiotic
prescription form in all admitted neonates in our unit from
September 2017 to August 2021. MS Excel and SPSS software
were used to tabulate and calculate the data.
Results: During the study a total of 5170 neonates were
admitted to the SNCU. The figures show the neonatal
admissions and relation of antibiotic usage to neonatal
mortality. There was a significant decrease in antibiotic
consumption (22.2% to 4.9% to 2.2% to 3.6%). There was
significant decrease in total antibiotic days (1179 vs 196 vs 158
vs 254). A significant reduction (p-value < 0.001) in antibiotic
consumption in pre and post intervention phase and also
in the years post intervention phase. Also the death rate in
infants with also reduced with the introduction of antibiotic
policy (p<0.001). The proportion of infants staying for >24
hours reduced significantly with the introduction of antibiotic
policy. There was a significant reduction in the cost to the unit
and cost per patient.
Conclusion: A simple use of antibiotic prescription and strict
adherence to its compliance is likely to reduce antibiotic
usage and result in reduction in neonatal mortality and
hospital duration.
Biography
Damera Yadaih Working as a consultant pediatrician at District Head Quarters Hospital, Nalgonda since 25 years. Working in SNCU from 2008 as civil surgeon, hod. Instrumental in establishing 1st NICU at District Hospital, Nalgonda in 2008. He is working to strengthen the FBNC in Telangana State to reduce NMR. Discharged 10,000 babies till date, Discharged 800 babies < 1500gm, smallest baby discharged 650gm, 28wk GA, 1st of its kind in any District Hospital.
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