ºÚÁÏÍø

Daniel Tennant

Affiliated to Professor of Biochemistry in the Institute of Metabolism and Systems Research (IMSR), situated on the second floor of the Institute of Biomedical Research.

Biography

Professor Daniel Tennant is a Professor of Biochemistry in the Institute of Metabolism and Systems Research (IMSR), situated on the second floor of the Institute of Biomedical Research. He uses stable isotope tracers to investigate changes in the use of nutrients in conditions where oxygen is limiting (hypoxia), or in the presence of genetic mutations that induce a hypoxia-like response. Dan applies the fundamental knowledge gained from these research projects to understand the pathogenesis of diseases where changes in oxygenation play a role; in particular, cancer.

Publications

Manipulating the HIF Pathway in Renal Transplantation, Current Progress and Future Developments

Renal transplantation is the gold standard treatment for end stage renal disease; however, there are currently not enough suitable organs to meet a growing demand. The Hypoxia Inducible Factor (HIF) pathway comprises a number of oxygen sensitive transcription factors which activate cellular protective functions. Allografts from cadaveric organs mak... Read More»

Alexander Hollis, Kamlesh Patel, Tom Smith, Jay Nath, Daniel Tennant, Andrew Ready and Christian Ludwig

Review Article: J Clin Exp Transplant 2016, 1:110

DOI:

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article