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Introduction:
Treponema pallidum, Hepatitis B Viruses (HBV) and Human
Immuno Virus (HIV) shares common transmission mechanisms
and their co-infection increase the risk of HIV transmission, HIV
treatment failure and treatment associated adverse among people
receiving Anti-Retroviral Therapy (ART). No documented data on
the extent of Treponema pallidum, Hepatitis B Viruses and their
associated risk factors of infections among people receiving ART
at Batu City of Ethiopia.
Objective:
To assess prevalence of Syphilis, HBV and associated factors
among adults attending ART service at Batu City.
Methods:
Four hundred two patients on ART were randomly selected from
health care facility in Batu town from June 1 to August 30, 2021.
Data was collected using structured questionnaire. Five ml whole
blood was collected and plasma was separated for detecting
Treponema pallidum and HBV by an enzyme-linked immune
sorbent assay. Data were entered into Epi-Info-7 then exported to
SPSS version 21 for cleaning and analysis. Descriptive statistics
was used to explore participants� characteristics. The association
between the predictors and outcome variables was assessed using
logistic regression model.
Results:
The prevalence of Syphilis and HBV among people receiving
ART was 11.2% and 16% respectively. Multiple sexual partners
(AOR=7.38, 95% CI: 2.85,19.1), non-condom uses (AOR=5.83,
95% CI: 1.04,32.54), were significantly associated with of Syphilis
and HBV among people receiving ART while drug injection is also
the predictor of HBV infection (AOR=7.59, 95% CI: 2.72,21.19).
Conclusion:
The prevalent sero-positivity of Syphilis and HBV among people
receiving ART in Batu city highlights the necessity of regular
screening for these infections and giving awareness on associated
prevention.
Biography
Girma Mulisa is a PhD student at Addis Ababa University and employee of Adama Hospital Medical College at the rank of assistant professor in Medical Microbiology. He is interested and work research on infectious diseases and drug resistance, coinfection and treatment challenge, synergy of infectious disease and chronic disease. He also teach and advancing medical students and muster students in microbiology.
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