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Imaging Findings of a Rare Aggressive Breast Cancer Subtype: Metaplastic Carcinoma of the Breast (E-MPBC): Metaplastic
breast carcinoma (MPBC) is one of the rarest and generally poorly differentiated invasive breast carcinomas. According to
our knowledge MPBC tend to show more benign imaging features, such as round, lobular, oval shape with a predominantly
circumscribed contour. We analyzed 65 patients with pathologically proven MPBC between 2004 and 2016. We reviewed
patients� medical files and breast imaging records of the all patients. Patients ranged in age from 25 to 88 years (median, 53
years) and 16 patients were younger than 40 years-old. The most common mammographic findings were round shape, micro
lobulated margin and high density masses. The most frequent sonographic presentations of MPBC were round shape, angular
margin which partially indistinct, hypoechoic and heterogeneous echo pattern and no posterior feature masses. MRI was
performed in 7 patients, and all lesions were presented as masses rather than non-mass enhancements. Six of the lesions showed
irregular or speculated margins. Signal intensity-time curves were type-II or type-III. DWI was obtained in 3 patients and the
lesions showed diffusion restriction in 2 patients. In conclusion, well-recognizing the findings of MPBC is very important.
Because, according to previously reported series this aggressive, high grade tumor can display more benign imaging feature.
This appearance can cause misdiagnosis as benign breast lesion especially in young women. Although the lesions demonstrate
benign or moderately malign feature, MPBC should be kept in mind in differential diagnosis for large palpable breast masses.
Biography
Hale Aydin has graduated from Ankara University School of Medicine, Ankara and completed residency from Baskent University School of Medicine Ankara (Turkey). She is a Radiologist with sub-specialty expertise in breast imaging, and she has been serving as breast Radiologist at Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara. Her research interests are focused on the use of imaging methods on breast cancers.