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Effect of Orlistat on Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) in Wistar Rats
Context: Orlistat is one of the few anti-obesity drugs that have been approved by FDA. It reduces the lipid absorption by 30% in its therapeutic dose by means of reversible inhibition of gastrointestinal lipases. Objective: Since vitamin K (a lipid soluble vitamin) is important in the synthesis of factors 2, 7, 9 and 10 of the coagulation cascade, ... Read More»
Mohammad Mahdi Tavana, Taha Yegani and Saeid Hajiaghajani
Research Article: J Obes Weight Loss Ther 2015, 5: 263
DOI:
Abstract Peer-reviewed Full Article Peer-reviewed Article PDF
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