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Abstract

Until recently, when endoscopic screening or surveillance revealed high-grade displasia in Barrettesophagus, the standard treatment was esophagectomy, a procedure associated with considerable morbidity and mortality. In recent years, endoscopic techniques have been developed to ablate or resect dysplastic Barrett mucosa with far less morbidity tan esophagectomy and with virtually no mortality. Endoscopic ablation techniques deliver thermal orpho to chemical energy to the esophageal mucosa with the intent of destroying the Barrettmetaplasia, and ablation techniques do not provide a tissue specimen for histologic. Barrettmetaplasia also can be removed by endoscopic mucosal resection (EMR), in which large segments of esophageal mucosa and sub-mucosa are resected with a diathermic snare, and submitted for histologic examination. Endoscopic mucosal resection can be therapeutic (because it removes neoplastic mucosa), and EMR provides invaluable information regarding the depth of tumor involvement (T stage). Endoscopic mucosal resection (EMR) is an endoscopic therapeutic proposal in which the dysplastic epithelium is removed, thus making it possible for a definitive histologic diagnosis and treatment.

Biography

Email: barretozu@yahoo.com