ISSN: 2161-069X
Journal of Gastrointestinal & Digestive System
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Helicibacter infection among dyspeptic and non-dyspeptic HIV patient at Yeka Health Center: Case control study
16th International Conference on Gastroenterology and Digestive Disorders
Getachew Seid
Ethiopia
Posters & Accepted Abstracts: J Gastrointest Dig Syst
DOI:
Abstract
Background: Helicobacter pylori are a potent engenderer of urease. HIV infected patients experience many forms of opportunistic infections, including gastrointestinal symptoms. The exact role of H. pylori infection among HIV infected patients in causing gastrointestinal symptoms such as dyspepsia remains obscure. There are circumscribed data regarding H. pylori infection in HIV positive patients in cognation to CD4 count in our region and country. There for we aimed to assess the prevalence of H. pylori infection utilizing stool antigen among dyspeptic and non-dyspeptic HIV patients and its cognation with CD4 T cell count. Methods: A case control study enrolling 370 study participants was conducted from January- June 2017. Socio-demographic and clinical data were amassed and 3 milliliter blood was drawn aseptically for the CD4+T cell count and complete blood count. Stool samples were accumulated for H. pylori stool antigen test. Data ingression and analysis was done utilizing SPSS version 20.confidence level of 95%was used statistical significance. Results: A total of 185 cases and 185 controls were participated in the study. H. pylori antigen was detected in 117 (31.62%) of the total participants. The prevalence of H. pylori infection of cases and control was 60/185 (32.43%) and 57/185 (30.81%), respectively (AOR=1.097, 95% CI: 0.689-1.747, p=0.697). In both case and control groups, no significant association was observed in the prevalence of H. pylori with age, family size, educational status, marital status, toilet use habit, occupation, alcohol drinking, cigarette smoking and khat chewing (p>0.05). In both case and control group H. pylori infection was higher in patients with CD4 T cell count greater than 200 cells/渭l. Conclusion: The prevalence of H. pylori infection was slightly higher among cases than control patients. The infection was not significantly associated with social, demographic and behavioral factors while it was higher in patients with higher CD4 T cell count. The observed prevalence of H. pylori stool antigen positivity necessitates the need to diagnose it in patients with higher CD4 T cell count and thus minimize the clinical consequences of infection.Biography
E-mail: Dr_gm18@yahoo.com
