ISSN: 2165-7904
Journal of Obesity & Weight Loss Therapy
黑料网
Our Group organises 3000+ Global Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ 黑料网 Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
黑料网 Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers
Citations : 2305
Indexed In
- Index Copernicus
- Google Scholar
- Open J Gate
- Genamics JournalSeek
- Centre for Agriculture and Biosciences International (CABI)
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- SWB online catalog
- CABI full text
- Cab direct
- Publons
- Geneva Foundation for Medical Education and Research
- Euro Pub
- University of Bristol
- Pubmed
- ICMJE
Useful Links
Recommended Journals
Related Subjects
Share This Page
About stability of a bladder cancer model under stochastic perturbations
5th Asian Obesity Specialists & Endocrinologists Annual Meeting
Shaikhet Leonid and Bunimovich-Mendrazitsky Svetlana
Tel Aviv University, Israel Ariel University, Israel
Posters & Accepted Abstracts: J Obes Weight Loss Ther
DOI:
Abstract
The method of stability investigation under stochastic perturbations of mathematical models of various types of epidemics, in particular, of the model of social obesity epidemic, was successfully used for investigation of cancer models. In this work the model of bladder cancer is investigated. Bladder cancer (BC) is 7th most common cancer (the 4th most common for men) with approximately 356,000 new cases each year and more than 145,000 deaths per year. Our model describes the treatment effects of the Bacillus Calmette-Gu�?漏rin (BCG) bacteria. Based on previous study, we have developed a new model with adding delay in the immune response to BCG injection and special adaptation to new knowledge about the BCG immunotherapy. The model characterizes the dynamics of the interactions between the four different biological components (BCG bacteria within the bladder (B), effector T-lymphocytes, mostly CTLs that react to BCG and to tumor antigens (E), tumor cells infected with BCG (Ti) and tumor cells that are not infected by BCG (Tu)) and is described by the system of four non-linear differential equations with a variable delay and stochastic perturbations of the type of white noise. The stability investigation of the considered model is based on the general method of Lyapunov functionals construction that was proposed and developed by V. Kolmanovskii and L. Shaikhet during last two decades.Biography
Email: leonid.shaikhet@usa.net
