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ISSN: 2161-0711

Journal of Community Medicine & Health Education
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Effect of radiation on deoxyribose nucleic acid (DNA): The fundamental blueprint for all of the bodys structures

Joint Event on 3rd World Congress on Medical Sociology & Public Health & International Conference on Public health and Epidemic diseases

Raymond Limen Njinga

North-West University, South Africa

Posters & Accepted Abstracts: J Community Med Health Educ

DOI:

Abstract
External or internal sources of radiation may have some impact on the living tissues. The functions of all living tissue are carried out by molecules. These molecules are combinations of different types of atoms which are bonded by chemical bonds. They depends upon their composition, structure or shape. Radiation exposure to a certain dosage might alter or break the chemical bond between two carbon atoms and change the composition or structure. Of all the molecules in the body, the most crucial is the deoxyribose nucleic acid (DNA) which encodes the blueprint in each cell as a long sequence of molecules wound around proteins and packed into structures called chromosomes within the cell nucleus. In this study we investigate the effect of indirect action on the DNA due to free radical from ionize water molecules. The free radical reacts with other DNA molecules as it seeks to restore a stable configuration of electrons thereby causing biological effects. From this studies, a dose of about 100 gray would cause the cell not to perform its function while a mean lethal dose of 2 gray would cause the cell not to reproduce, but still performs its other functions. However, it was revealed that if the irradiation dose from the free radicals in water does not kill the cell it would create an error in the DNA blueprint. This may contributes to eventual loss of control of cell division. Hence, the cell begins dividing uncontrollably causing cancer which might be long or short term depending on the level of dosage and time of exposure. Excess dose may also alter the DNA resulting to cell mutations that occur in germ cells called genetic or heritable effects and at least 1,300 diseases are known to be caused by a mutation.
Biography

E-mail: rlnjinga@gmail.com

 

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