Journal of Community Medicine & Health Education
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Malnutrition assessed through phase angle and its relation to prognosis in patients with compensated liver cirrhosis: A prospective cohort study
World Congress on Public Health and Nutrition
Astrid Ruiz-Marg�?隆in Ricardo U. Mac�?颅as-Rodr�?颅guez, Andr�?漏s Duarte-Rojo, Silvia L. R�?颅os-Torres, �?聛ngeles Espinosa-Cuevas and Aldo Torre
Insituto Nacional de Ciencias M�?漏dicas y Nutrici�?鲁n Salvador Zubir�?隆n, Mexico
Posters & Accepted Abstracts: J Community Med Health Educ
DOI:
Abstract
Background: Malnutrition is a frequent complication of cirrhosis and it has been associated to more severe disease and development of complications. Phase angle is a bedside reliable tool for nutritional assessment based on conductivity properties of body tissues. �?麓 Aim: To evaluate the association between malnutrition assessed through phase angle and mortality in patients with liver cirrhosis. Methods: We performed a prospective cohort study in a tertiary care centre; 249 patients were enrolled with 48 months of follow-up. Clinical, nutritional (malnutrition = phase angle 芒�?陇 4.9芒�?娄) and biochemical evaluations were performed. Student芒�?�?s t-test and 2 method were used as appropriate. Kaplan芒�?�?Meier curves and multivariate Cox regression were used to evaluate mortality. Results: Mean follow-up was 33.5 months. Survival analysis showed higher mortality in the malnourished group compared to the well-nourished group (p = 0.076), Kaplan芒�?�?Meier curves were further stratified according to compensated and decompensated status showing higher mortality in compensated patients according to Child芒�?�?Pugh (p = 0.002) and Model for End-Stage Liver Disease score (p = 0.008) when malnutrition was present. Multivariate analysis showed that malnutrition was independently associated with mortality (HR = 2.15, 1.18芒�?�?3.92). Conclusions: In our cohort, malnutrition was independently associated with mortality. This is the first study showing higher mortality in malnourished compensated cirrhotic patients.Biography
Email: ruizm.astrid@gmail.com
