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A Review: Molecular mechanism of CCl4 induced hepatotoxicity
The liver is vital to metabolic activities making it susceptible to liver injury. CCl4induced hepatotoxicity is widely studied in model organisms to assess liver damage as it directly mimics the damage in humans. CCl4 activation is ascribed to various cytochrome (CYP) 2E1, CYP2B1 or CYP2B2, and possibly CYP3A, resulting in the trichloromethyl radic... Read More»
: BCP
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