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Background: Aspartyl-Asparaginyl-Β-Hydroxylase (ASPH) is a downstream target of insulin and IGF signaling and promotes cell motility for liver remodeling and repair. ASPH functions in part by activating Notch and HIF-1α. PPAR agonists can ameliorate steatohepatitis, hepatic insulin resistance, and reduced ASPH expression in experimental a... Read More»
Diana L Borgas, Chetram Deochand, Ming Tong and Suzanne M de la Monte
Research Article: Biochem Physiol 3: 145
DOI:
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