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Abstract

In the reviewed articles, quinpirole is used as a dopamine D2 and D3 receptor agonist to induce persistent behavior in animal models. Dopamine has been related to perseverative behavior also has been related with the perseption of pain and relief. The perseverative behavior was observed in an open field with objects of different shapes and sizes. The main structures studied with this methodology are the orbitofrontal cortex, striatum, thalamus, basolateral amygdala and nucleus accumbens. The animal models studied comply with the face, predictive and construct validity. We think this topic is important because the content of the article shows the right structure and methodology also how to evaluate and compare the information in different articles this method can be applied at any topic; we have focused in the face, predictive and construct validity. It is important to mention that this reviewed article had and extensive search in the website of Pubmed although there were only a few information of the topic which it is a reason for us to continue investigating and providing new information related.

Biography

Abraham Flores Vargas has completed his medical studies from Universidad Autonoma de Estado de México and recently stared residency in anesthesiology from Hospital General de México “Dr. Eduardo Liceaga “ at Mexico city and signed up in the medical program of the Universidad Nacional Autonoma de México. He has done his research social service last year publishing a review article named OCD in animal models using quinpirole as dopaminergic inductor of perseverative behavior at the “Revista medica del Hospital General de México” last year now-a-days working in the continuation of the second article related with quinpirole. He is with total willingness to continue investigating and bringing in issues related to anesthesiology.

Email: remediosvargas@hotmail.com