黑料网

Abstract

Background & Aim: Fibromyalgia is musculoskeletal pain disorder that impacts well-being and interrupts daily activities. The present study evaluated the stability and change of key fibromyalgia symptoms over a 2-year period. Methods: Patients from an existing fibromyalgia registry were mailed seven validated questionnaires evaluating physical functioning, fatigue, daily limitations, pain, sleep levels, mental and physical well-being, and cognitive abilities. Of the 1303 patients contacted, 858 returned a completed survey. Approximately two years later, the patients who completed the baseline survey were sent a second and identical survey. A total of 450 patients returned the follow-up survey and are included in these analyses. Results: Paired t-tests showed a significant change in fibromyalgia impact, fatigue, mental and physical health, pain, mood, and cognitive abilities (ps<.05) over the two-year period. Statistically larger decreases in mental health and increases in pain, as well as, vitality were observed. The remainder of the changes, while statistically significant, was smaller. Conclusions: Although the results of our study suggest a slight trend toward improvement in several of the measures, changes were small to modest in size; and not significant according to minimum clinically significant difference (MCID) criteria over the two years of this study. Our study sheds light on the longer-term prognosis for worsening or improving symptoms in fibromyalgia. Specifically, our findings suggest that the long-term trajectory for change, in either direction, is considerably more stable and unchanging than existing research might suggest.

Biography